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Lisdexamfetamine Side Effects

Although most people tolerate lisdexamfetamine well, there are potential side effects of the medication. Some of the most common lisdexamfetamine side effects include a decreased appetite, insomnia, and headaches. Typically, the side effects are minor and can easily be treated. However, some side effects of lisdexamfetamine (such as hallucinations, shortness of breath, and suicidal thoughts) may require immediate medical care.

An Introduction to Lisdexamfetamine Side Effects

As with any medicine, side effects are possible with lisdexamfetamine dimesylate (Vyvanse™). However, not everyone who takes the medication will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with lisdexamfetamine. Your healthcare provider can discuss a more complete list of lisdexamfetamine side effects with you.)
 

Common Side Effects of Lisdexamfetamine

Lisdexamfetamine has been studied thoroughly in clinical trials. In these studies, the side effects that occur in a group of people taking the drug are documented and then compared to the side effects that occur in another group of people not taking the medicine. As a result, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
 
In these studies, the most common side effects of lisdexamfetamine included:
 
  • A decreased appetite -- in up to 39 percent of people
  • Insomnia -- up to 27 percent (see Vyvanse and Insomnia)
  • Dry mouth -- up to 26 percent
  • Stomach pain (abdominal pain) -- up to 12 percent
  • Headaches -- up to 12 percent
  • Irritability -- up to 10 percent.
     
Other common lisdexamfetamine side effects (occurring in 2 to 9 percent of children) included:
 
  • Diarrhea
  • Feeling jittery
  • Shakiness (tremor)
  • Increased sweating
  • Nausea
  • Vomiting
  • Fever
  • Weight loss (see Vyvanse and Weight Loss)
  • Dizziness
  • Drowsiness
  • Mood changes.
     
Stimulants (such as lisdexamfetamine) can temporarily slow down the growth rate in children. This slowing of growth is usually small (less than an inch and less than two pounds), and children usually catch up to within normal limits in time.
 
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Lisdexamfetamine Dimesylate

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