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Levomilnacipran Side Effects

Some people who take levomilnacipran may develop side effects during treatment, such as constipation, nausea, or excessive sweating. Fortunately, in most cases, these reactions are minor and tend to be easy to treat. However, if you have thoughts of harming yourself, confusion, or any unusual bruising, contact your healthcare provider right away, as urgent treatment may be necessary.


An Introduction to Side Effects of Levomilnacipran

Just like any medicine, levomilnacipran (Fetzima™) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in many cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with levomilnacipran. Your healthcare provider can discuss a more complete list with you.)

Serious Levomilnacipran Side Effects

Some side effects of levomilnacipran are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Thoughts of suicide or of harming yourself (see Fetzima and Suicide)
  • Any unusual changes in mood or behavior
  • High blood pressure
  • A fast, forceful, or fluttering heartbeat
  • Difficulty passing urine
  • Eye pain
  • Changes in vision
  • Signs of low blood sodium (hyponatremia), such as:
    • Confusion
    • Problems concentrating
    • Memory problems
    • Headache
    • Unsteadiness or falling
    • Weakness
    • Dizziness or fainting
    • Hallucinations
    • Seizures
  • Signs of serotonin syndrome (a rare but dangerous problem associated with medications that affect serotonin), such as:
    • Confusion or other mental changes
    • A rapid heart rate
    • Nausea, vomiting, or diarrhea
    • Hallucinations
    • High or low blood pressure
    • Muscle stiffness
    • Fever, sweating, or shivering
    • Incoordination
    • Twitching muscles
    • Shakiness
    • Agitation
    • Seizures
    • Coma
  • Signs of mania, which may include:
    • Extreme feelings of happiness or elation
    • Much more energy than usual
    • Problems sleeping
    • Racing thoughts or ideas
    • Talking very quickly or more than usual
    • Extreme irritability
  • Seizures
  • Any unusual bleeding or bruising
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.
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