Because L-methylfolate is a dietary supplement, there are no clearly established dosing guidelines for the various uses of this natural product. This is an active form of folic acid, so dosages for L-methylfolate are typically based on the dosing guidelines for folic acid. L-methylfolate usually comes in tablet or capsule form and is taken once or twice daily.
An Introduction to Dosing With L-MethylfolateThere are no clearly established dosing recommendations for many natural products and dietary supplements, including L-methylfolate. There are reasonable dosing guidelines for some L-methylfolate uses, but most recommendations are based on the guidelines for folic acid. However, at this time, it is not entirely clear how to convert folic acid doses into L-methylfolate doses.
L-Methylfolate Dosage Guidelines for Pregnancy
The recommended folic acid dosage for pregnant women is 600 mcg per day. Many prenatal vitamins contain as much as 1000 mcg (1 mg). A similar L-methylfolate dosage (600 mcg to 1000 mcg) is most likely sufficient.
Prenatal vitamins that contain L-methylfolate usually have between 600 mcg (0.6 mg) and 1130 mcg (1.13 mg) of the vitamin. Some prenatal vitamins contain both folic acid and L-methylfolate. Normally, additional L-methylfolate above and beyond what is found in prenatal vitamins is not needed during pregnancy.
However, pregnant women who have previously had a child with a history of neural tube defects are usually instructed to take a higher folic acid dosage, typically around 4 mg (4000 mcg) per day. These women may need more L-methylfolate if they choose to take it over folic acid. Talk to your healthcare provider about the best dose of L-methylfolate for your pregnancy.