Imipramine and Breastfeeding
If you are taking imipramine and breastfeeding at the same time, the medication can be passed through breast milk to your nursing infant. But the levels of imipramine that are passed through breast milk and into the baby's blood appear to be very low or undetectable. However, you should still be sure to talk with your healthcare provider before breastfeeding while on imipramine.
Imipramine hydrochloride (Tofranil®) and imipramine pamoate (Tofranil PM®) pass through breast milk in low amounts. Due to the possible harmful effects that imipramine might have on the breastfeeding infant, you should talk with your healthcare provider before taking imipramine while breastfeeding.
The levels of imipramine that are passed through breast milk appear to be low. Most studies found very low (or undetectable) amounts of imipramine in the blood of the breastfed babies. Studies also showed no negative effects on the development of the breastfed babies whose mothers were taking imipramine.
You should talk with your healthcare provider about imipramine and breastfeeding. This is because everyone's situation is different, and your healthcare provider understands your situation best. Based on what you want and expect and your current health situation, you and your healthcare provider can make a shared decision about imipramine and breastfeeding for your particular situation.