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Iloperidone Dosage

For iloperidone to work properly, it must be taken as prescribed. The recommended starting dose of iloperidone for schizophrenia will depend on several factors, such as how you respond to iloperidone, other medications you are taking, and other medical conditions you may have. In most cases, your healthcare provider will start you on a low iloperidone dosage and then slowly increase the dose.

Iloperidone Dosage: An Introduction

The dose of iloperidone (Fanapt®) your healthcare provider recommends will vary, depending on a number of factors, including:
  • How you respond to iloperidone
  • Other medications you are taking
  • Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically instructs you to do so.

Iloperidone Dosing for Schizophrenia

In order to reduce the risk of low blood pressure when standing up too quickly (known as orthostatic hypotension), iloperidone is started at a low dose and slowly increased. The standard recommended dosage for iloperidone is as follows:
  • Day 1 -- iloperidone 1 mg twice daily
  • Day 2 -- iloperidone 2 mg twice daily
  • Day 3 -- iloperidone 4 mg twice daily
  • Day 4 -- iloperidone 6 mg twice daily
  • Day 5 -- iloperidone 8 mg twice daily
  • Day 6 -- iloperidone 10 mg twice daily
  • Day 7 -- iloperidone 12 mg twice daily.
Some people may not need the maximum dosage. If you have stopped taking iloperidone for more than three days, it is usually recommended that you start back with a low dosing and increase the dosage slowly (as was done initially).
If you take certain other medications, the recommended dosage of iloperidone is reduced by half (see Drug Interactions With Iloperidone for more information). Similarly, if you are known to metabolize certain medications more slowly than normal (laboratory tests have shown that you are a "CYP 2D6 poor metabolizer"), the recommended dosage is reduced by half.
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Iloperidone Drug Information

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