Drug Interactions With Guanfacine ER

Alcohol, Depakote, and blood pressure medications are among the substances that can cause drug interactions with guanfacine ER. These reactions can increase the risk of side effects and lead to problems such as low blood pressure and extreme drowsiness. To ensure a safe treatment process, make sure your healthcare provider is aware of all medications you are taking.

Guanfacine ER Drug Information

An Overview of Guanfacine ER Interactions

Guanfacine ER (Intuniv^™) can potentially interact with several other medications. Some of the medicines that may lead to drug interactions include but are not limited to:

Alcohol or other substances or medications that cause drowsiness
Blood pressure medications
CYP3A4 inhibitor medications, such as:
- Amprenavir (Agenerase^®)
- Atazanavir (Reyataz^®)
- Clarithromycin (Biaxin^®)
- Conivaptan (Vaprisol^®)
- Darunavir (Prezista^®)
- Delavirdine (Rescriptor^®)
- Fosamprenavir (Lexiva^®)
- Imatinib (Gleevec^®)
- Indinavir (Crixivan^®)
- Isoniazid
- Itraconazole (Sporanox^®)
- Ketoconazole (Nizoral^®)
- Lopinavir and ritonavir (Kaletra^®)
- Miconazole
- Nefazodone (Serzone^®)
- Nelfinavir (Viracept^®)
- Nicardipine (Cardene^®)
- Posaconazole (Noxafil^®)
- Quinidine
- Ritonavir (Norvir^®)
- Saquinavir (Fortovase^®, Invirase^®)
- Telithromycin (Ketek^®)
- Voriconazole (VFEND^®)

Valproate medications, such as:
- Delayed-release valproic acid (Stavzor^®)
- Divalproex (Depakote^®)
- Divalproex ER (Depakote ER^®)
- Valproic acid (Depakene^®).

(Drug Interactions With Guanfacine ER Continued: Page 2)