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Drug Interactions With Fluvoxamine CR

Ramelteon (Rozerem)
Taking ramelteon and fluvoxamine CR together can increase the level of ramelteon in your blood, which could increase your risk of side effects. These two medications should not be taken together.
 
SSRI or SNRI Medications
Combining fluvoxamine CR with other SSRI or SNRI medications can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome, as it can be dangerous.
 
St. John's Wort
Taking fluvoxamine CR with St. John's wort can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome, as it can be quite dangerous.
 
Tacrine (Cognex)
Combining tacrine and fluvoxamine CR can increase the level of tacrine in your blood, possibly increasing your risk of side effects. Your healthcare provider may need to decrease your tacrine dosage to prevent this interaction from occurring.
 
Theophylline
Fluvoxamine CR can increase the level of theophylline in your blood, possibly increasing your risk of side effects. Your healthcare provider should monitor the level of theophylline in your blood, especially when you are starting or stopping fluvoxamine CR.
 
Tizanidine (Zanaflex)
Taking tizanidine and fluvoxamine CR together can increase the level of tizanidine in your blood, which could increase your risk of side effects. These two medications should not be taken together.
 
Tramadol (Rybix ODT, Ryzolt, Ultram, Ultram ER) or Tramadol and Acetaminophen (Ultracet)
Taking fluvoxamine CR with a tramadol can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome, as it can be quite dangerous.
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