Drug Interactions With Dexmethylphenidate

Some of the drugs that can potentially interact with dexmethylphenidate include SSRI antidepressants, pressors, and warfarin. Drug interactions with dexmethylphenidate can possibly increase your risk of bleeding, alter the levels of some drugs in your blood, or cause an increase in side effects like increased blood pressure and heart rate. Also, because of the risk of life-threatening side effects, you should not take MAO inhibitors along with dexmethylphenidate unless your healthcare provider specifically tells you to do so.

 

Drug Interactions With Dexmethylphenidate: An Overview

Dexmethylphenidate hydrochloride (Focalin®) can potentially interact with several drugs. Some of the drugs that may lead to dexmethylphenidate interactions include:
 
  • Clonidine (Catapres®)
     
  • Monoamine oxidase inhibitors (MAOIs), including:
o Dopamine (Intropin®)
o Dobutamine (Dobutrex®)
o Epinephrine (Adrenalin®, EpiPen®)
o Norepinephrine (Levophed®)
  • Warfarin (Coumadin®, Jantoven®).
     
(Drug Interactions With Dexmethylphenidate Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;