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Drug Interactions With Dexmethylphenidate Extended-Release

Interactions With Dexmethylphenidate Extended-Release Explained

The following sections explain in detail the potentially negative reactions that can occur when dexmethylphenidate extended-release is combined with any of the drugs listed above.
 
Antacids or Acid Reducers
Reducing the acid level of the stomach could change the way dexmethylphenidate extended-release is released. It is not known how different antacids or acid reducers might affect dexmethylphenidate extended-release. Talk with your healthcare provider before taking dexmethylphenidate extended-release and antacids or acid reducers together.
 
MAO Inhibitors
Taking dexmethylphenidate extended-release and MAO inhibitors together can cause life-threatening side effects, such as very high blood pressure. Do not take dexmethylphenidate extended-release and MAO inhibitors together unless your healthcare provider specifically tells you to. Do not take dexmethylphenidate extended-release if you have taken an MAO inhibitor within the past two weeks.
 
Pressors
Taking dexmethylphenidate extended-release and pressors together can cause an increase in side effects, particularly increased blood pressure and increased heart rate. Your healthcare provider may need to monitor your heart rate and blood pressure closely and adjust your doses of these drugs if necessary.
 
Seizure Medications
Taking dexmethylphenidate extended-release with seizure medications can increase the amount of the seizure medication in the blood, perhaps increasing your risk of side effects. Your healthcare provider may need to decrease your dose of the seizure medication.
 
SSRI Antidepressants
Taking dexmethylphenidate extended-release with an SSRI antidepressant can increase the amount of the antidepressant in your blood, perhaps increasing your risk of side effects. Your healthcare provider may need to decrease your dose of the antidepressant.
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