Drug Interactions With Desvenlafaxine

People are generally recommended to avoid drinking alcohol while taking desvenlafaxine. Drug interactions may also occur if the depression medication is taken with cimetidine, haloperidol, monoamine oxidase inhibitors, or nonsteroidal anti-inflammatory drugs, among other things. To help prevent drug interactions with desvenlafaxine, tell your healthcare provider about all other medicines you are taking before beginning treatment.

 

An Introduction to Drug Interactions With Desvenlafaxine

Desvenlafaxine (Pristiq™) can potentially interact with a number of medicines. Some of the medicines that can lead to drug interactions with desvenlafaxine include:
 
  • Alcohol
  • Anticoagulant or antiplatelet medications, such as:
 
    • Aspirin (Bayer® and others)
    • Clopidogrel (Plavix®)
    • Heparin or heparin-like products, such as:
 
      • Dalteparin (Fragmin®)
      • Enoxaparin (Lovenox®)
      • Tinzaparin (Innohep®)
 
    • Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:
 
 
    • Warfarin (Coumadin®, Jantoven®)
 
 
 
  • Other selective serotonin reuptake inhibitor (SSRI) or serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressants, such as:
 
 
 
 
 
 
(Drug Interactions With Desvenlafaxine Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;