Talk with your healthcare provider prior to taking this medication if you have:
- Bipolar disorder or a family history of bipolar disorder (also known as manic depression)
- A history of suicide attempts or suicidal thoughts
- Heart problems
- Seizures or epilepsy
- High cholesterol or high triglycerides
- High blood pressure (hypertension)
- A history of stroke
- A bleeding disorder
- Low sodium levels in the blood (hyponatremia)
- Glaucoma (an eye condition)
- Liver disease, including liver failure or cirrhosis
- Kidney problems, including kidney failure (renal failure)
- Any allergies, including allergies to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Pristiq and Pregnancy)
- Breastfeeding (see Pristiq and Breastfeeding).
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Desvenlafaxine to learn more, including information on who should not take the drug.)