Clozaril Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
Clozaril is combined with any of the drugs listed above.
Benzodiazepines
Taking Clozaril with a benzodiazepine can increase your risk of dangerous side effects. Talk to your healthcare provider before combining these medications.
Blood Pressure Medications
Certain Antibiotics or Antifungals
Taking Clozaril with certain antibiotics or antifungals can increase the level of Clozaril in your blood, which may increase your risk of side effects. Your healthcare provider may need to lower your
Clozaril dosage to prevent this interaction from occurring.
Certain Anticonvulsants
Taking Clozaril with certain anticonvulsants (
seizure medications) can decrease the level of Clozaril in your blood, perhaps making it less effective. Your healthcare provider may need to increase your Clozaril dosage to prevent this from occurring.
Certain Antidepressants
Combining Clozaril with certain
antidepressants can increase the level of Clozaril in your blood, possibly increasing your risk of
Clozaril side effects. Your healthcare provider may need to lower your Clozaril dose as a result.
Certain Arrhythmia Medications
Taking Clozaril with certain arrhythmia medications can increase the level of both Clozaril and the arrhythmia medication in your blood, which may increase your risk of side effects. Depending on your situation, your healthcare provider may need to lower your dose of Clozaril and the arrhythmia medication.
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