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Clozaril Drug Interactions

Clozaril Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Clozaril is combined with any of the drugs listed above.
 
Benzodiazepines
Taking Clozaril with a benzodiazepine can increase your risk of dangerous side effects. Talk to your healthcare provider before combining these medications.
 
Blood Pressure Medications
Clozaril can cause low blood pressure (hypotension). Your healthcare provider should monitor your blood pressure closely if you take blood pressure medications with Clozaril.
 
Certain Antibiotics or Antifungals
Taking Clozaril with certain antibiotics or antifungals can increase the level of Clozaril in your blood, which may increase your risk of side effects. Your healthcare provider may need to lower your Clozaril dosage to prevent this interaction from occurring.
 
Certain Anticonvulsants
Taking Clozaril with certain anticonvulsants (seizure medications) can decrease the level of Clozaril in your blood, perhaps making it less effective. Your healthcare provider may need to increase your Clozaril dosage to prevent this from occurring.
 
Certain Antidepressants
Combining Clozaril with certain antidepressants can increase the level of Clozaril in your blood, possibly increasing your risk of Clozaril side effects. Your healthcare provider may need to lower your Clozaril dose as a result.
 
Certain Arrhythmia Medications
Taking Clozaril with certain arrhythmia medications can increase the level of both Clozaril and the arrhythmia medication in your blood, which may increase your risk of side effects. Depending on your situation, your healthcare provider may need to lower your dose of Clozaril and the arrhythmia medication.
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Clozaril Drug Information

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