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What Is Chlordiazepoxide and Amitriptyline Used For?

Chlordiazepoxide and amitriptyline is used for the treatment of depression associated with anxiety. The combination medicine helps to relax muscles, reduce anxiety, and stop seizures. Since antidepressants can increase the risk of suicidal thoughts and behavior in young people, the medication is not approved for use in children or adolescents. At this time, there are no off-label chlordiazepoxide and amitriptyline uses.

What Is Chlordiazepoxide and Amitriptyline Used For? -- An Overview

Chlordiazepoxide and amitriptyline (Limbitrol®) is a prescription medication that is used to treat depression associated with anxiety. As the name implies, it is a combination of two medications: chlordiazepoxide (Librium®), an anxiety medication, and amitriptyline (Elavil®), an antidepressant.
Many people think of anxiety and depression as being opposites. However, it is common for people to have both depression and anxiety at the same time.

Understanding Depression and Anxiety

Depression is more than just "feeling sad." Common symptoms of depression include:
  • Changes in sleep (sleeping too much or not enough)
  • Eating too much or too little (and weight gain or weight loss)
  • Having little interest in things that you used to enjoy
  • Physical pain
  • Feeling hopeless or worthless
  • Suicidal thoughts.
Most people with depression also have anxiety symptoms, which can include:
  • Feeling shaky, jittery, or nervous
  • Feeling tense, fearful, or apprehensive
  • Avoiding certain places or activities because of fear
  • A pounding or racing heart or trouble catching your breath
  • Unexplained sweating or trembling
  • Fear of losing control, going crazy, or dying.
Chlordiazepoxide and amitriptyline is approved for treating moderate to severe depression associated with moderate to severe anxiety. As mentioned, it is a combination of an antidepressant and an anxiety medication. When these medications are used together, they usually work more effectively and more quickly, compared to either medication alone.
Some symptoms usually improve more quickly than others. These symptoms (which often begin to improve in the first week) include:
  • Insomnia
  • Feelings of guilt or worthlessness
  • Agitation
  • Anxiety
  • Suicidal thinking
  • Loss of appetite.
Recognizing Symptoms of ADHD

Drug Information on Chlordiazepoxide and Amitriptyline

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