Among the drugs that can potentially interact with bupropion are beta blockers, antipsychotic medications, monoamine oxidase inhibitors (MAOIs), and certain arrhythmia medications. Bupropion drug interactions can cause unwanted side effects, alter the levels of some drugs in your blood, and cause high blood pressure, among other things. You should be sure to talk with your healthcare provider about any drug interactions with bupropion that may apply to you.
Bupropion hydrochloride (Wellbutrin®) can potentially interact with a number of other medicines. Some of the medicines that can lead to bupropion interactions include: