Drug Interactions With Bupropion
Bupropion Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when bupropion is combined with any of the drugs listed above.
It is not recommended that you drink alcohol while taking bupropion. Combining alcohol and bupropion together may cause unwanted side effects (see Bupropion and Alcohol). However, since stopping alcohol abruptly while taking bupropion can increase your risk of seizures, talk with your healthcare provider before you stop drinking alcohol.
Taking bupropion with other antidepressants may affect the level of bupropion and the other antidepressants in your blood, increasing your risk of side effects. Also, taking bupropion with other antidepressants may increase your risk of seizures. Talk with your healthcare provider before combining bupropion with other antidepressant medications.
Taking bupropion and amantadine together may increase your risk of side effects. Your healthcare provider may decide to start you at a lower bupropion dose if you are taking amantadine.
Bupropion can raise the levels of some antipsychotic medications in your blood, increasing your risk of side effects. Also, taking bupropion with antipsychotic medications may increase your chances of developing seizures. Talk with your healthcare provider before taking these medications together.