Bupropion and Weight Loss

Bupropion can cause weight loss in some people. The medicine has several side effects that can contribute to weight loss, including nausea and a loss of appetite. Although weight loss can be a good thing for some people, it can be a problem for others. If you are taking bupropion and weight loss becomes a problem, let your healthcare provider know.

Bupropion HCl

An Overview of Bupropion and Weight Loss

Bupropion hydrochloride (Wellbutrin^®) is a prescription medicine used for the treatment of depression (also known as major depression or clinical depression). There are a number of possible side effects of bupropion, and weight loss appears to be one of them. For some people, this may be a good thing. For a lot of people, however, unintended weight loss can be a problem.

How Common Is Weight Loss With Bupropion?

In previous studies, up to 28 percent of people taking bupropion lost more than five pounds. Although weight loss may be a desirable side effect for some people, too much weight loss can be a problem.

Why Does Bupropion Cause Weight Loss?

It is not entirely clear why bupropion can cause weight loss.

Bupropion can often cause a loss of appetite, nausea, and vomiting, which may contribute to weight loss. Often, these side effects go away with time. However, you should be sure to let your healthcare provider know if these side effects do not go away. Also, since weight gain can be a symptom of depression, treating the depression can lead to weight loss.

If you are experiencing too much weight loss with bupropion, be sure to let your healthcare provider know.