Drug Interactions With Bupropion XL (Cont.)

 
Nelfinavir
Nelfinavir may interact with bupropion XL, although there have been no reports of such an interaction in actual patients. Your healthcare provider may need to monitor you more closely and may need to adjust your dose of these medications.
 
Nicotine Patches
If bupropion XL is taken while using nicotine patches, this can cause high blood pressure. Your healthcare provider should monitor your blood pressure if you are taking these medications together.
 
Orphenadrine
Orphenadrine may interact with bupropion XL, although there have been no reports of such an interaction in actual patients. Your healthcare provider may need to monitor you more closely and may need to adjust your dose of these medications.
 
Ritonavir
Ritonavir may interact with bupropion XL, although there have been no reports of such an interaction in actual patients. Your healthcare provider may need to monitor you more closely and may need to adjust your dose of these medications.
 
Steroids
Taking bupropion XL with intravenous or oral steroids can increase your risk of seizures. Talk to your healthcare provider before taking these medications together.
 
Theophylline
Combining bupropion XL with theophylline can increase your risk of seizures. Talk to your healthcare provider before taking these medications together.
 
Thiotepa
Thiotepa may interact with bupropion XL, although there have been no reports of such an interaction in actual patients. Your healthcare provider may need to monitor you more closely and may need to adjust your dose of these medications.
 

Final Thoughts on Drug Interactions With Bupropion XL

It is possible that not all drug interactions with bupropion XL were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific interactions that may apply to you.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;