Bupropion XL Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
bupropion XL is combined with any of the drugs listed above.
Alcohol
Alcohol and
bupropion XL should not be combined. Taking the two together may cause unwanted side effects
(see Wellbutrin XL and Alcohol). However, because stopping alcohol abruptly while taking the medication can increase your risk of
seizures, talk to your healthcare provider before you stop drinking alcohol.
Other Antidepressants
Taking bupropion XL with other
antidepressants may affect the level of bupropion XL and the other antidepressant in your blood, increasing your risk of side effects. Also, taking bupropion XL with other antidepressants may increase your risk of
seizures. Talk with your healthcare provider before combining bupropion XL with other antidepressant medications.
Amantadine
Combining bupropion XL and
amantadine may increase your risk of side effects. Your healthcare provider may decide to start you at a lower dose of bupropion XL if you are taking amantadine to avoid this drug interaction.
Antipsychotic Medications
Bupropion XL can increase the level of some
antipsychotic medications in your blood, which may increase your risk of side effects. Also, taking bupropion XL with antipsychotic medications may increase your chance of seizures. Talk with your healthcare provider before taking these medications together.
Previous
