Mental Health Channel
Topics & Medications
Quicklinks
Related Channels

Drug Interactions With Bupropion SR

Levodopa (Parcopa, Sinemet, Sinemet CR, Stalevo)
Taking bupropion SR and levodopa together may increase your risk of side effects. Your healthcare provider may decide to start you at a lower bupropion SR dose if you are taking levodopa.
 
Monoamine Oxidase Inhibitors (MAOIs)
You should not take bupropion SR if you have taken an MAOI within the past 14 days, due to an increased risk of dangerous side effects.
 
Nelfinavir (Viracept)
While it is thought that nelfinavir may interact with bupropion SR, there have been no reports of such an interaction in actual patients. If you are taking nelfinavir along with bupropion SR, your healthcare provider may need to monitor you more closely and may need to adjust your doses of these medications.
 
Nicotine Patches (NicoDerm CQ)
Taking bupropion SR while using nicotine patches can cause high blood pressure. Your healthcare provider should monitor your blood pressure if you are taking these medications together.
 
Orphenadrine (Norflex)
While it is thought that orphenadrine may interact with bupropion SR, there have been no reports of such an interaction in actual patients. If you are taking orphenadrine along with bupropion SR, your healthcare provider may need to monitor you more closely and may need to adjust your doses of these medications.
 
Ritonavir (Norvir) or Lopinavir and Ritonavir (Kaletra)
Ritonavir (whether taken alone or with lopinavir) may increase the metabolism of bupropion SR, leading to decreased levels of bupropion SR in the blood and possibly to decreased effectiveness. Check with your healthcare provider before taking such medications together. You may need a higher bupropion SR dosage, although the maximum recommended dosage should not be exceeded, even if you are taking ritonavir.
  
Steroids (Prednisone, Methylprednisolone)
Taking bupropion SR with intravenous or oral steroids can increase your risk of seizures. Talk with your healthcare provider before taking these medications together.
 
Tamoxifen (Nolvadex)
At least theoretically, bupropion SR could cause tamoxifen to be less effective. Check with your healthcare provider before taking these medications together.
  
Theophylline
Taking bupropion SR with theophylline can increase your risk of seizures. Talk with your healthcare provider before taking bupropion SR and theophylline together.
6 Ways Dogs Help People With Depression

Bupropion HCl SR

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2017 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.