Drug Interactions With Buproban
Combining Buproban and levodopa may increase your risk of side effects. To prevent this, your healthcare provider may decide to start you at a lower Buproban dosage if you are taking levodopa.
Monoamine Oxidase Inhibitors
You should not take Buproban if you have taken an MAOI within the past 14 days, due to the increased risk of dangerous side effects.
While it is thought that nelfinavir may interact with Buproban, there have been no reports of such an interaction in actual patients. To be safe, your healthcare provider may choose to monitor you more closely and may need to adjust your doses of these medications.
Taking Buproban while using nicotine patches can cause high blood pressure (hypertension). As a result, your healthcare provider should monitor your blood pressure if you are taking these medications together.
While it is thought that orphenadrine may interact with Buproban, there have been no reports of such an interaction in actual patients. If you are taking orphenadrine along with Buproban, your healthcare provider may need to monitor you more closely and may choose to adjust your doses of these medications.
Ritonavir (Norvir) or Lopinavir and Ritonavir (Kaletra)
Ritonavir (whether taken alone or with lopinavir) may increase the metabolism of Buproban, leading to decreased levels of Buproban in the blood and possibly to decreased effectiveness. Check with your healthcare provider before taking such medications together. You may need a higher Buproban dosage, although the maximum recommended dosage should not be exceeded, even if you are taking ritonavir.
Taking Buproban with intravenous (IV) or oral steroids can increase your risk of seizures. Talk with your healthcare provider before taking these medications together.
At least theoretically, Buproban could cause tamoxifen to be less effective. Check with your healthcare provider before taking these medications together.