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Side Effects of Amphetamine-Dextroamphetamine Extended Release

As with any medication, there are potential side effects of amphetamine-dextroamphetamine extended release, including weight loss, emotional changes, and loss of appetite. When side effects do occur, they are generally minor and easily treated. If you experience more serious side effects while taking this drug (such as hallucinations, seizures, or suicidal thoughts), be sure to alert your healthcare provider immediately.

Amphetamine-Dextroamphetamine Extended Release Side Effects: An Introduction

As with any medicine, there are possible side effects of amphetamine-dextroamphetamine extended release (Adderall XR®). However, not everyone who takes this drug will experience side effects. In fact, most people tolerate the medication well. When side effects do occur, in most cases they are minor, meaning they require no treatment or are easily treated by you or your healthcare provider.
(The side effects discussed below are not a complete list of side effects reported with this medication. Your healthcare provider can discuss a more complete list of possible side effects with you.)

Common Amphetamine-Dextroamphetamine Extended Release Side Effects

Amphetamine-dextroamphetamine extended release has been thoroughly studied in clinical trials, with many people having been evaluated. In these studies, the side effects occurring in a group of people taking the drug are always documented and compared to the side effects that occur in a similar group of people not taking the medicine. Based on these studies, the most common amphetamine-dextroamphetamine extended release side effects include:
  • Loss of appetite (anorexia) -- occurring in up to 36 percent of people
  • Dry mouth -- in up to 35 percent
  • Difficulty sleeping (insomnia) -- in up to 27 percent
  • Headaches -- in up to 26 percent
  • Abdominal pain (or stomach pain) -- in up to 14 percent
  • Temporary increase in blood pressure -- in up to 11 percent
  • Weight loss -- in up to 11 percent (see Adderall and Weight Loss)
  • Emotional changes -- in up to 9 percent
  • Nausea, upset stomach, or vomiting -- in up to 8 percent
  • Dizziness -- in up to 7 percent
  • Diarrhea -- in up to 6 percent
  • Feeling of weakness (asthenia) -- in up to 6 percent
  • Increased heart rate (tachycardia) -- in up to 6 percent
  • Infection, including urinary tract infection (UTI) -- in up to 5 percent
  • Fever -- in up to 5 percent
  • Heartburn -- in up to 2 percent.
Amphetamine-dextroamphetamine extended release can also cause a temporary slowing of growth in children. This slowing of growth is usually small (less than an inch and less than two pounds), and children usually catch up to within normal limits in time.
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Amphetamine and Dextroamphetamine Extended Release Info

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