Drug Interactions With Amphetamine-Dextroamphetamine Extended Release (Cont.)

Amphetamine-Dextroamphetamine Extended Release Interactions Explained

 
Acetazolamide (Diamox)
Taking amphetamine-dextroamphetamine extended release and acetazolamide together can increase the amount of amphetamine-dextroamphetamine extended release in the blood, resulting in possible side effects. Your healthcare provider may need to decrease your dose of the medications.
 
Ammonium Chloride
Taking amphetamine-dextroamphetamine extended release and ammonium chloride together can decrease the amount of amphetamine-dextroamphetamine extended release in the blood, perhaps making it less effective. Your healthcare provider may need to increase your dose of the medications.
 
Certain Antacids
Taking amphetamine-dextroamphetamine extended release with very high doses of certain antacids (such as calcium carbonate) can increase the amount of amphetamine-dextroamphetamine extended release in the blood, resulting in possible side effects. This is probably not a problem with occasional use of antacids. Your healthcare provider may need to adjust your dose of these medications.
 
Certain Sleep Medications
Taking amphetamine-dextroamphetamine extended release with certain sleep medications, such as diphenhydramine, can decrease the effectiveness of the sleep aid. Your healthcare provider may need to adjust your dose of these medications.
 
Chlorpromazine (Thorazine)
Taking amphetamine-dextroamphetamine extended release and chlorpromazine together can change the way the brain reacts to amphetamine-dextroamphetamine extended release, making it less effective. Your healthcare provider may need to adjust your dose of these medications.
 
Ethosuximide (Zarontin)
Taking amphetamine-dextroamphetamine extended release and ethosuximide together can cause ethosuximide to be absorbed in the body more slowly, perhaps making it less effective. Your healthcare provider may need to adjust your dose of these drugs.
(Drug Interactions With Amphetamine-Dextroamphetamine Extended Release Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;