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Drug Interactions With Amoxapine

Amoxapine Interactions Explained

The following sections explain in detail the negative interactions that can occur when amoxapine is combined with any of the drugs listed above.
 
Alcohol
Amoxapine may enhance the effects of alcohol. This can lead to an increased risk for suicidal thoughts and other amoxapine overdose symptoms. Make sure to talk with your healthcare provider about drinking alcohol while taking amoxapine.
 
Anticholinergic Medications
Taking amoxapine with anticholinergic medications may cause increased side effects. Talk to your healthcare provider before using these medications together, as your dosages may need to be reduced. Since some of these types of medicines are found in over-the-counter medicines, do not treat yourself for the common cold, a cough, or allergies without first talking to your healthcare provider.
 
Arrhythmia Medications
Taking amoxapine with arrhythmia medications can increase your risk of a dangerous arrhythmia called QT prolongation. Also, certain arrhythmia medications can increase the level of amoxapine in your blood, increasing your risk of side effects. Talk to your healthcare provider before taking these medications together.
 
Barbiturates
Taking amoxapine with barbiturates can increase the risk of side effects of both amoxapine and barbiturates, such as drowsiness or dizziness. Your healthcare provider may need to adjust your dose of these medications.
 
Cimetidine (Tagamet)
Taking amoxapine with cimetidine can increase the level of amoxapine in your blood, increasing your chance of side effects. Your healthcare provider may need to adjust your dose of these medications.
 
Monoamine Oxidase Inhibitors (MAOIs)
Taking amoxapine with MAOIs can increase your chance of developing dangerous side effects. Do not take amoxapine if you have taken an MAOI within the past two weeks.
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Amoxapine Drug Information

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